Purpose Apelin is an adipokine that plays a role in the regulation of many biological
functions in mammals including the neuroendocrine, cardiovascular, immune systems,
glucose homeostasis and obesity. It can act via autocrine, paracrine, endocrine, and
exocrine signaling. We aimed to identify the role of apelin pathophysiology of diabetes.
Material/methods 37 male Wistar Albino rats aged 8–10 weeks were divided in four
experimental groups as: control group (C) control+ apelin group (C+ A), diabetic group (D)�…