The neuroanatomy of autism: a voxel-based whole brain analysis of structural scans

F Abell, M Krams, J Ashburner, R Passingham…�- …, 1999 - journals.lww.com
AUTISM is a biological disorder which affects social cognition, and understanding brain
abnormalities of the former will elucidate the brain basis of the latter. We report structural
MRI data on 15 high-functioning individuals with autistic disorder. A voxel-based whole
brain analysis identified grey matter differences in an amygdala centered system relative to
15 age-and IQ-matched controls. Decreases of grey matter were found in anterior parts of
this system (right paracingulate sulcus, left inferior frontal gyrus). Increases were found in�…