Kisspeptin neurons are critical components of the neuronal network controlling the activity of
the gonadotropin-releasing hormone (GnRH) neurons. A variety of genetically-manipulated
mouse models have recently facilitated the study of the electrical activity of the two principal
kisspeptin neuron populations located in the rostral periventricular area of the third ventricle
(RP3V) and arcuate nucleus (ARN) in acute brain slices. We discuss here the mechanisms
and pathways through which kisspeptin neurons regulate GnRH neuron activity. We then�…