The effect of lifestyle modification and cardiovascular risk factor reduction on erectile dysfunction: a systematic review and meta-analysis

BP Gupta, MH Murad, MM Clifton…�- Archives of internal�…, 2011 - jamanetwork.com
Background Erectile dysfunction (ED) shares similar modifiable risks factors with coronary
artery disease (CAD). Lifestyle modification that targets CAD risk factors may also lead to
improvement in ED. We conducted a systematic review and meta-analysis of randomized
controlled trials evaluating the effect of lifestyle interventions and pharmacotherapy for
cardiovascular (CV) risk factors on the severity of ED. Methods A comprehensive search of
multiple electronic databases through August 2010 was conducted using predefined criteria�…