Sample results66 results in the last year.
Significance of visual scene‐based learning in the hippocampal systems across mammalian species
The hippocampus and its associated cortical regions in the medial temporal lobe
play essential roles when animals form a cognitive map and use it to achieve their
goals. As the nature of map‐making involves sampling different local views of the�…
play essential roles when animals form a cognitive map and use it to achieve their
goals. As the nature of map‐making involves sampling different local views of the�…
Episodic future thinking as a promising intervention for substance use disorders: a reinforcer pathology perspective
Abstract Purpose of Review Reinforcer Pathology theory (RP) identifies that a short
temporal window leads to an excessive preference for substance reinforcers
because of their temporal dynamics. Episodic future thinking (EFT), or envisioning�…
temporal window leads to an excessive preference for substance reinforcers
because of their temporal dynamics. Episodic future thinking (EFT), or envisioning�…
Newer modalities in the management of Alzheimer's dementia along with the role of aducanumab and lecanemab in the treatment of its refractory cases
Alzheimer's disease (AD) is a common neurological condition characterized by a
gradual and progressive decline in memory, language, emotion, and cognition. It
mainly affects elderly people. Due to the effects of AD, pharmaceutical medications�…
gradual and progressive decline in memory, language, emotion, and cognition. It
mainly affects elderly people. Due to the effects of AD, pharmaceutical medications�…
Associative and predictive hippocampal codes support memory-guided behaviors
Episodic memory involves learning and recalling associations between items and
their spatiotemporal context. Those memories can be further used to generate
internal models of the world that enable predictions to be made. The mechanisms�…
their spatiotemporal context. Those memories can be further used to generate
internal models of the world that enable predictions to be made. The mechanisms�…
Visuotactile integration facilitates mirror-induced self-directed behavior through activation of hippocampal neuronal ensembles in mice
Remembering the visual features of oneself is critical for self-recognition. However,
the neural mechanisms of how the visual self-image is developed remain unknown
because of the limited availability of behavioral paradigms in experimental animals�…
the neural mechanisms of how the visual self-image is developed remain unknown
because of the limited availability of behavioral paradigms in experimental animals�…
Terahertz photons improve cognitive functions in posttraumatic stress disorder
Posttraumatic stress disorder (PTSD) is a serious psychosis leading to cognitive
impairment. To restore cognitive functions for patients, the main treatments are based
on medication or rehabilitation training but with limited effectiveness and strong side�…
impairment. To restore cognitive functions for patients, the main treatments are based
on medication or rehabilitation training but with limited effectiveness and strong side�…
Recalling gist memory depends on CA1 hippocampal neurons for lifetime retention and CA3 neurons for memory precision
Why some of us remember events more clearly than others and why memory loses
precision over time is a major focus in memory research. Here, we show that the
recruitment of specific neuroanatomical pathways within the medial temporal lobe�…
precision over time is a major focus in memory research. Here, we show that the
recruitment of specific neuroanatomical pathways within the medial temporal lobe�…
Mapping the spatial transcriptomic signature of the hippocampus during memory consolidation
Memory consolidation involves discrete patterns of transcriptional events in the
hippocampus. Despite the emergence of single-cell transcriptomic profiling
techniques, mapping the transcriptomic signature across subregions of the�…
hippocampus. Despite the emergence of single-cell transcriptomic profiling
techniques, mapping the transcriptomic signature across subregions of the�…
KAT6A deficiency impairs cognitive functions through suppressing RSPO2/Wnt signaling in hippocampal CA3
Intellectual disability (ID) affects~ 2% of the population and ID-associated genes are
enriched for epigenetic factors, including those encoding the largest family of histone
lysine acetyltransferases (KAT5-KAT8). Among them is KAT6A, whose mutations�…
enriched for epigenetic factors, including those encoding the largest family of histone
lysine acetyltransferases (KAT5-KAT8). Among them is KAT6A, whose mutations�…
Tebuconazole mediates cognitive impairment via the microbe-gut-brain axis (MGBA) in mice
Tebuconazole, one of the most widely used triazole fungicides, is reported to
potentially pose a risk of inducing neurological disorders in human beings.
Considering the increasing exposure, whether it could influence cognitive function�…
potentially pose a risk of inducing neurological disorders in human beings.
Considering the increasing exposure, whether it could influence cognitive function�…