Create alert

Cells are continually exposed to reactive oxygen species (ROS) generated during
cellular metabolism. Apoptosis, necrosis, and autophagy are biological processes
involving a feedback cycle that causes ROS molecules to induce oxidative stress. To�…

Ascorbic acid is a redox regulator in many physiological processes. Besides its
antioxidant activity, many intriguing functions of ascorbic acid in the expression of
immunoregulatory genes have been suggested. Ascorbic acid acts as a co‐factor for�…

Ascorbate is a small antioxidant molecule essential for the proper development and
function of the brain. Ascorbate is transported into the brain and between brain cells
via the Sodium vitamin C co-transporter 2 (SVCT2). This review provides an in-depth�…

Photosynthetic organisms, fungi, and animals comprise distinct pathways for vitamin
C biosynthesis. Besides this diversity, the final biosynthetic step consistently involves
an oxidation reaction carried out by the aldonolactone oxidoreductases. Here, we�…

Vitamin C (L-ascorbic acid) is an essential nutrient for human health, and its
deficiency has long been known to cause scurvy. Sodium-dependent vitamin C
transporters (SVCTs) are responsible for vitamin C uptake and tissue distribution in�…

Vitamin C is an essential enzyme cofactor and antioxidant with pleiotropic roles in
human physiology. Circulating vitamin C concentrations are lower in people with
diabetes mellitus, suggesting a higher dietary requirement for the vitamin. We�…

Strawberry (Fragaria� ananassa) fruits are an excellent source of L-ascorbic acid
(AsA), a powerful antioxidant for plants and humans. Identifying the genetic
components underlying AsA accumulation is crucial for enhancing strawberry�…

Vitamin C plays important roles as a cofactor in many enzymatic reactions and as an
antioxidant against oxidative stress. As some mammals including humans cannot
synthesize vitamin C de novo from glucose, its uptake from dietary sources is�…

The present investigation aimed to evaluate the effect of popping and malting on
nutritional characteristics in millets. Five genotypes each of sorghum, finger millet
and pearl millet were analyzed after popping and malting process. The�…

Uric acid is the main means of nitrogen excretion in uricotelic vertebrates (birds and
reptiles) and the end product of purine catabolism in humans and a few other
mammals. While uricase is inactivated in mammals unable to degrade urate, the�…