Sample results415 results in the last year.

Sex steroids and the female brain across the lifespan: insights into risk of depression and Alzheimer's disease

C Barth, A Crestol, AMG de Lange, LAM Galea�- The Lancet Diabetes &�…, 2023
Despite widespread sex differences in prevalence and presentation of numerous
illnesses affecting the human brain, there has been little focus on the effect of
endocrine ageing. Most preclinical studies have focused on males only, and clinical�…

Inflammation in multiple sclerosis: Consequences for remyelination and disease progression

L Klotz, J Antel, T Kuhlmann�- Nature Reviews Neurology, 2023
Despite the large number of immunomodulatory or immunosuppressive treatments
available to treat relapsing–remitting multiple sclerosis (MS), treatment of the
progressive phase of the disease has not yet been achieved. This lack of successful�…

Schizophrenia: from neurochemistry to circuits, symptoms and treatments

OD Howes, BR Bukala, K Beck�- Nature Reviews Neurology, 2024
Schizophrenia is a leading cause of global disability. Current pharmacotherapy for
the disease predominantly uses one mechanism—dopamine D2 receptor blockade—
but often shows limited efficacy and poor tolerability. These limitations highlight the�…

Developmental trajectory of transmission speed in the human brain

D van Blooijs, MA van den Boom, JF van der Aar…�- Nature Neuroscience, 2023
The structure of the human connectome develops from childhood throughout
adolescence to middle age, but how these structural changes affect the speed of
neuronal signaling is not well described. In 74 subjects, we measured the latency of�…

The use of opioids in the management of chronic pain: synopsis of the 2022 updated US Department of Veterans Affairs and US Department of Defense clinical�…

F Sandbrink, JL Murphy, M Johansson, JL Olson…�- Annals of internal medicine, 2023
Description: In May 2022, leadership within the US Department of Veterans Affairs
(VA) and US Department of Defense (DoD) approved a joint clinical practice
guideline for the use of opioids when managing chronic pain. This synopsis�…

Nutrition in school-age children: a rationale for revisiting priorities

JM Saavedra, AM Prentice�- Nutrition Reviews, 2023
Middle childhood and early adolescence have received disproportionately low levels
of scientific attention relative to other life stages, especially as related to nutrition and
health. This is partly due to the justified emphasis on the first 1000 days of life, and�…

A neuroecosocial perspective on adolescent development

S Choudhury, B Piera Pi-Sunyer, SJ Blakemore�- Annual Review of Developmental�…, 2023
Adolescence is a period of life that encompasses biological maturation and profound
change in social roles. It is also a period associated with the onset of mental health
problems. The field of developmental cognitive neuroscience has advanced our�…

Developmental neuroimaging of cognitive flexibility: update and future directions

LB Kupis, LQ Uddin�- Annual Review of Developmental Psychology, 2023
Cognitive flexibility, or the ability to mentally switch between tasks according to
changing environmental demands, supports optimal life outcomes, making it an
important executive function to study across development. Here we review the�…

Association of white matter volume with brain age classification using deep learning network and region wise analysis

R Pilli, T Goel, R Murugan, M Tanveer�- Engineering Applications of Artificial�…, 2023
Structural magnetic resonance imaging (sMRI) has been used to examine age-
related neuroanatomical changes in the human brain. In the present work, a pre-
trained deep learning model and an ensemble deep random vector functional link�…

A critical review of research on executive functions in sport and exercise

P Furley, LM Sch�tz, G Wood�- International Review of Sport and Exercise�…, 2023
ABSTRACT The investigation of Executive Functions (EF) has become a trending
topic of investigation in sport science. This critical review provides a comprehensive
synthesis of the underlying theory and the typical methodology (and problems with�…