Most relevant results57 results in the last year.
Oral decitabine–cedazuridine versus intravenous decitabine for myelodysplastic syndromes and chronic myelomonocytic leukaemia (ASCERTAIN): a registrational�…
Background The DNA methyltransferase inhibitors azacitidine and decitabine for
individuals with myelodysplastic syndromes or chronic myelomonocytic leukaemia
are available in parenteral form. Oral therapy with similar exposure for these�…
individuals with myelodysplastic syndromes or chronic myelomonocytic leukaemia
are available in parenteral form. Oral therapy with similar exposure for these�…
ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype
We have previously demonstrated synergy between ICOS costimulation (IVAX;
ICOSL-transduced B16-F10 cellular vaccine) and CTLA-4 blockade in antitumor
therapy. In this study, we employed CyTOF and single-cell RNA sequencing and�…
ICOSL-transduced B16-F10 cellular vaccine) and CTLA-4 blockade in antitumor
therapy. In this study, we employed CyTOF and single-cell RNA sequencing and�…
Higher docosahexaenoic acid levels lower the protective impact of eicosapentaenoic acid on long-term major cardiovascular events
Introduction Long-chain omega-3 polyunsaturated fatty acids (OM3 PUFA) are
commonly used for cardiovascular disease prevention. High-dose eicosapentaenoic
acid (EPA) is reported to reduce major adverse cardiovascular events (MACE);�…
commonly used for cardiovascular disease prevention. High-dose eicosapentaenoic
acid (EPA) is reported to reduce major adverse cardiovascular events (MACE);�…
Electrically Reconfigurable Phase‐Change Transmissive Metasurface
Programmable and reconfigurable optics hold significant potential for transforming a
broad spectrum of applications, spanning space explorations to biomedical imaging,
gas sensing, and optical cloaking. The ability to adjust the optical properties of�…
broad spectrum of applications, spanning space explorations to biomedical imaging,
gas sensing, and optical cloaking. The ability to adjust the optical properties of�…
Immunomodulation profile of the biosimilar trastuzumab MYL-1401O in a bioequivalence phase I study
The initial Phase-I single centre, single dose, randomized, double-blind, cross-over
study was planned to assess the pharmacokinetic and pharmacodynamic
bioequivalence of the trastuzumab biosimilar (MYL-1401O) compared to the�…
study was planned to assess the pharmacokinetic and pharmacodynamic
bioequivalence of the trastuzumab biosimilar (MYL-1401O) compared to the�…
Monolithic beam combined quantum cascade laser arrays with integrated arrayed waveguide gratings
Quantum cascade lasers (QCLs) are ubiquitous mid-infrared sources owing to their
flexible designs and compact footprints. Manufacturing multiwavelength QCL chips
with high power levels and good beam quality is highly desirable for many�…
flexible designs and compact footprints. Manufacturing multiwavelength QCL chips
with high power levels and good beam quality is highly desirable for many�…
Design of continuously tunable varifocal metalenses
Active metasurfaces with tunable optical properties enable reconfigurable or
programmable photonic systems that can swiftly adapt to different functional needs.
Realizing continuous tuning of phase-gradient metasurfaces, however, remains�…
programmable photonic systems that can swiftly adapt to different functional needs.
Realizing continuous tuning of phase-gradient metasurfaces, however, remains�…
Kenaf fibres from Burkina Faso valorization in the improvement of durability, thermal properties and fracture behavior of adobes amended with cement
This study aimed to improve the thermal properties and fracture behavior of adobes.
A mixture of clay, cement (2 wt%) and kenaf fibres (1.5 and 3 cm long) was used to
manufacture the adobes. The physico-chemical and microstructural properties of the�…
A mixture of clay, cement (2 wt%) and kenaf fibres (1.5 and 3 cm long) was used to
manufacture the adobes. The physico-chemical and microstructural properties of the�…
Acceptance and User Experiences of a Wearable Device for the Management of Hospitalized Patients in COVID-19–Designated Wards in Ho Chi Minh City, Vietnam�…
Background Wearable devices have been used extensively both inside and outside
of the hospital setting. During the COVID-19 pandemic, in some contexts, there was
an increased need to remotely monitor pulse and saturated oxygen for patients due�…
of the hospital setting. During the COVID-19 pandemic, in some contexts, there was
an increased need to remotely monitor pulse and saturated oxygen for patients due�…
Uncovering Spatial Patterns of Residential Settlements, Segregation, and Vulnerability of Urban Seniors Using Geospatial Analytics and Modeling Techniques
We harnessed the analytical power of geospatial analysis and modeling techniques,
pioneering a novel approach to studying the spatial distribution of households with at
least one senior aged 65 or over, known as senior households (SHHs). We�…
pioneering a novel approach to studying the spatial distribution of households with at
least one senior aged 65 or over, known as senior households (SHHs). We�…
No less relevant results in the last month.