We present evidence for cosmic-ray acceleration at the forward shock in Tycho's supernova
remnant (SNR) from three X-ray observables:(1) the proximity of the contact discontinuity to …

… The software we used is described in Hughes & Birkinshaw (1998). It is based on a maximum
likelihood figure-of-merit function derived for Poisson-distributed data and allows for the …

We introduce a million second observation of the supernova remnant Cassiopeia A with the
Chandra X-Ray Observatory. The bipolar structure of the Si-rich ejecta (northeast jet and …

… Ghavamian, & JP Hughes 2002, in preparation), we expect the most rapid changes in the
thermodynamic state of the postshock gas to occur immediately behind the blast wave, and it is …

… 10 kyr) was attributed to the supernova (SN) explosion having occurred in a preexisting
interstellar cavity (Hughes et al. 1998). Einstein and ROSAT images revealed the broadband X-…

… ), while nearly all larger remnants are dominated by swept-up ambient medium (Hughes et
al. … of soft thermal emission and closely resembles the ASCA spectrum (Hughes et al. 1998). …

INTRODUCTION The rhesus macaque (Macaca mulatta) is one of the most widely used
nonhuman primate (NHP) models for studying human biology and disease. As a representative …

Cohesion establishment and maintenance are carried out by proteins that modify the activity
of Cohesin, an essential complex that holds sister chromatids together. Constituents of the …

… the NERC project; JP, RW, and JV designed the original experiments; EG, JP, and JV …
The team are members of the Wallace Initiative collaboration led by JP Competing interests: …

Elevated blood pressure is the leading heritable risk factor for cardiovascular disease
worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) …