Liver allograft rejection remains a significant cause of morbidity and graft failure in liver
transplant recipients. Rejection is caused by the recognition of non-self donor alloantigens by …

Background Treatment guidelines recommend a stepwise approach to primary biliary cholangitis:
all patients begin treatment with ursodeoxycholic acid (UDCA) monotherapy and those …

Backgrounds & Aims Primary biliary cholangitis (PBC) is a chronic liver disease in which
autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many …

Primary biliary cholangitis (PBC) is a cholestatic liver disease characterized by the destruction
of the small and medium bile ducts. Its pathogenesis is still unknown. Despite the genome …

Background & aims Obeticholic acid (OCA) is the second-line treatment approved for
patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to …

Driver’s stress affects decision-making and the probability of risk occurrence, and it is therefore
a key factor in road safety. This suggests the need for continuous stress monitoring. This …

The sample size is a crucial concern in scientific research and even more in behavioural
neurosciences, where besides the best practice it is not always possible to reach large …

The capability of monitoring user’s performance represents a crucial aspect to improve safety
and efficiency of several human-related activities. Human errors are indeed among the …

The capability of measuring specific neurophysiological and autonomic parameters plays a
crucial role in the objective evaluation of a human’s mental and emotional states. These …

Background & Aims Genome-wide association studies in primary biliary cholangitis (PBC)
have failed to find X chromosome (chrX) variants associated with the disease. Here, we …