… M�ller-Werdan engaged in clinical and experimental work on immunoglobulins in inflammation
and sepsis. With this respect, the following categories of financial interest existed or do …

Objective: Multiple organ dysfunction syndrome (MODS) is the sequential failure of several
organ systems after a trigger event, like sepsis or cardiogenic shock. Mortality rate is high, up …

In sepsis, systemic inflammatory response syndrome (SIRS), and multiorgan dysfunction
syndrome (MODS), a severe prognostically relevant cardiac autonomic dysfunction exists, as …

Inflammatory pathways are involved in the development of atherosclerosis. Interaction of vessel
wall cells and invading monocytes by cytokines may trigger local inflammatory processes…

The sympathetic-parasympathetic balance may be altered in critically ill patients. Assessment
of autonomic function provides information concerning prognosis, pathogenesis, and …

Age-related changes in body composition reflect an increased risk for disease as well as
disability. Bioimpedance analysis is a safe and inexpensive bed side method to measure body …

Myocardial depression in human sepsis was only unequivocally proven in the 1980s by the
group of Parrillo, who used nuclear imaging techniques to measure heart volumes and …

Objective: Multiple organ dysfunction syndrome (MODS) is a disease entity that carries a
high mortality rate. It is characterized by a sequential failure of several organ systems after a …

Aim Several clinical trials have demonstrated the antianginal and anti-ischemic efficacy of
ivabradine in combination with beta-blocker in patients with stable angina pectoris. The …

Cardiac hypertrophy and heart failure are frequently accompanied by elevated plasma levels
of tumor necrosis factorα(TNFα), the pathogenetic relevance of this finding being a matter …