Stimulator of interferon genes (STING) is a receptor in the endoplasmic reticulum that
propagates innate immune sensing of cytosolic pathogen-derived and self DNA 1 . The …

Kinobeads are a set of promiscuous kinase inhibitors immobilized on sepharose beads for
the comprehensive enrichment of endogenously expressed protein kinases from cell lines …

The demographic change and the decrease of care personnel lead to the discussion to
implement robots to support older adults. To ensure sustainable use, the solutions must be …

We present a one‐step Ugi reaction protocol for the expedient synthesis of photoaffinity
probes for live‐cell MS‐based proteomics. The reaction couples an amine affinity function with …

Due to demographic change, the increasing shortage of skilled professionals in the care sector,
and the desire of older adults to stay independent as long as possible, it is predicted that …

Introduction Patients with early-onset Alzheimer's disease (EOAD) experience seizures and
subclinical epileptiform activity, which may accelerate cognitive and functional decline. …

Polypharmacy increases the risk of unbearable side effects, drug–drug interactions, and
hospitalizations in geriatric patients. The iatrogenic risk of inadequate management of …

Global change impacts on the Earth System are typically evaluated using biome classifications
based on trees and forests. However, during the Cenozoic, many terrestrial biomes were …

Regular physical activity is a central protective factor for health. The promotion of physical
activity is an important issue, especially for ageing societies, to achieve benefits of health and …

In response to public fears surrounding an anticipated rise in youth crime, several forms of
punitive juvenile justice legislation were implemented during the “get tough” era of the 1980s …