O termo tiol ou sulfidril refere-se ao grupo SH. Os ti�is biol�gicos s�o reativos e ub�q�itos, e
t�m sido extensivamente estudados em v�rios sistemas biol�gicos, principalmente os …

Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …

The antioxidant activity of flavonoids is believed to increase when they are coordinated with
transition metal ions. However, the literature on this subject is contradictory and the outcome …

For human immunodeficiency virus (HIV)-infected patients, the 1990s were marked by the
introduction of highly active antiretroviral therapy (HAART) representing a new perspective of …

Iron is an essential metal for cell survival that is regulated by the peptide hormone hepcidin.
However, its influence on certain diseases is directly related to iron metabolism or …

Oxysterols are oxidized derivatives of cholesterol produced by enzymatic activity or non-enzymatic
pathways (auto-oxidation). The oxidation processes lead to the synthesis of about 60 …

Amniotic fluid (AF) was described as a potential source of mesenchymal stem cells (MSCs)
for biomedicine purposes. Therefore, evaluation of alternative cryoprotectants and freezing …

Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …

Aging is characterized by a progressive increase in oxidative stress, which favors lipid
peroxidation and the formation of cholesterol oxide derivatives, including 7β-hydroxycholesterol (…

Aging is defined as the accumulation of progressive organ dysfunction. There is much evidence
linking the involvement of oxidative stress in the pathogenesis of aging. With increasing …