TNFα has recently emerged as a regulator linking inflammation to cancer pathogenesis, but
the detailed cellular and molecular mechanisms underlying this link remain to be elucidated. …

Enhancer of Zeste homolog 2 (EZH2) is a methyltransferase that plays an important role in
many biological processes through its ability to trimethylate lysine 27 in histone H3. Here, we …

The rapid increase in the prevalence of overweight and obesity is becoming an important
health problem. Overweight and obesity may cause several metabolic complications, including …

Background The current strategies for prevention and treatment of insulin resistance and
type 2 diabetes are not fully effective and frequently accompanied by many negative effects. …

Objective: In this study, we exploited a VGG-16 deep convolutional neural network (DCNN)
model to differentiate papillary thyroid carcinoma (PTC) from benign thyroid nodules using …

The increasing prevalence of type 2 diabetes mellitus with its high morbidity and mortality
becomes an important health problem. The multifactorial etiology of type 2 diabetes mellitus is …

Regulatory T cell (Treg)-mediated immunosuppression represents one of the crucial tumor
immune evasion mechanisms and is a main obstacle for successful tumor immunotherapy. …

AIM: To investigate the apoptotic effects of melittin on SGC-7901 cells via activation of the
mitochondrial signaling pathway in vitro. METHODS: SGC-7901 cells were stimulated by …

Ecosystem water use efficiency (WUE) reflects the intimately coupled relationship between
the carbon and water cycles in terrestrial ecosystems. However, the inter-annual variation …

Genistein is one of the main components of soy-based foods, which are widely known for
their many benefits, including anti-cancer, anti-inflammatory, and antioxidant effects. In this …