Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux
of low molecular weight solutes (molecular weight up to 1,500) across the generally …

The term “mitochondrial permeability transition” (MPT) refers to an abrupt increase in the
permeability of the inner mitochondrial membrane to low molecular weight solutes. Due to …

The term mitochondrial permeability transition (MPT) is commonly used to indicate an abrupt
increase in the permeability of the inner mitochondrial membrane to low molecular weight …

Since 1929, when it was discovered that ATP is a substrate for muscle contraction, the
knowledge about this purine nucleotide has been greatly expanded. Many aspects of cell …

The impact of the mitochondrial permeability transition ( MPT ) on cellular physiology is well
characterized. In contrast, the composition and mode of action of the permeability transition …

Scaled sandbox models have successfully simulated the geometries and progressive
evolution of antiformal pop-up structures developed in a weak sedimentary cover above …

A large body of evidence indicates that mitochondrial dysfunction has a major role in the
pathogenesis of multiple cardiovascular disorders. Over the past 2 decades, extraordinary …

Reactive oxygen species (ROS) are highly reactive molecules, mainly generated inside
mitochondria that can oxidize DNA, proteins, and lipids. At physiological levels, ROS function as “…

The heterogenous subcellular distribution of a wide array of channels, pumps and exchangers
allows extracellular stimuli to induce increases in cytoplasmic Ca 2+ concentration ([Ca 2…

Protein phosphorylation controls many aspects of cell fate and is often deregulated in pathological
conditions. Several recent findings have provided an intriguing insight into the spatial …