Genetic variation in alcohol dehydrogenase and the beneficial effect of moderate alcohol consumption on myocardial infarction
LM Hines, MJ Stampfer, J Ma…�- …�England Journal of�…, 2001 - Mass Medical Soc
Background A polymorphism in the gene for alcohol dehydrogenase type 3 (ADH3 ) alters
the rate of alcohol metabolism. We investigated the relation among the ADH3 polymorphism, …
the rate of alcohol metabolism. We investigated the relation among the ADH3 polymorphism, …
Potentially harmful drug–drug interactions in the elderly: a review
LE Hines, JE Murphy�- The American journal of geriatric pharmacotherapy, 2011 - Elsevier
BACKGROUND: Elderly patients are vulnerable to drug interactions because of age-related
physiologic changes, an increased risk for disease associated with aging, and the …
physiologic changes, an increased risk for disease associated with aging, and the …
[HTML][HTML] Alternatively activated macrophages and collagen remodeling characterize the postpartum involuting mammary gland across species
…, J Monks, MS Lucia, RS Wilson, L Hines…�- The American journal of�…, 2010 - Elsevier
Recent pregnancy correlates with decreased survival for breast cancer patients compared
with non–pregnancy-associated breast cancer. We hypothesize that postpartum mammary …
with non–pregnancy-associated breast cancer. We hypothesize that postpartum mammary …
Cooperation of the ErbB2 receptor and transforming growth factor β in induction of migration and invasion in mammary epithelial cells
SE Seton-Rogers, Y Lu, LM Hines…�- Proceedings of the�…, 2004 - National Acad Sciences
MCF10A mammary epithelial cells form growth-arrested structures when cultured in three-dimensional
basement membrane gels. Activation of the receptor tyrosine kinase ErbB2 …
basement membrane gels. Activation of the receptor tyrosine kinase ErbB2 …
[HTML][HTML] Multiple and additive functions of ALDH3A1 and ALDH1A1: cataract phenotype and ocular oxidative damage in Aldh3a1 (-/-)/Aldh1a1 (-/-) knock-out mice
…, G Duester, BJ Day, J Huang, LM Hines…�- Journal of Biological�…, 2007 - ASBMB
ALDH3A1 (aldehyde dehydrogenase 3A1) is abundant in the mouse cornea but undetectable
in the lens, and ALDH1A1 is present at lower (catalytic) levels in the cornea and lens. To …
in the lens, and ALDH1A1 is present at lower (catalytic) levels in the cornea and lens. To …
Recommendations to improve the usability of drug-drug interaction clinical decision support alerts
Objective: To establish preferred strategies for presenting drug-drug interaction (DDI)
clinical decision support alerts. Materials and Methods: A DDI Clinical Decision Support …
clinical decision support alerts. Materials and Methods: A DDI Clinical Decision Support …
[HTML][HTML] Diet patterns and breast cancer risk in Hispanic and non-Hispanic white women: the Four-Corners Breast Cancer Study
…, C Sweeney, AR Giuliano, JS Herrick, L Hines…�- The American journal of�…, 2008 - Elsevier
Background There is a lower incidence of breast cancer among Hispanic women than
among non-Hispanic white women. Little is known about the role of diet in this difference. …
among non-Hispanic white women. Little is known about the role of diet in this difference. …
Ability of pharmacy clinical decision-support software to alert users about clinically important drug—drug interactions
KR Saverno, LE Hines, TL Warholak…�- Journal of the�…, 2011 - academic.oup.com
Objective Pharmacy clinical decision-support (CDS) software that contains drug–drug
interaction (DDI) information may augment pharmacists' ability to detect clinically significant …
interaction (DDI) information may augment pharmacists' ability to detect clinically significant …
Consensus recommendations for systematic evaluation of drug–drug interaction evidence for clinical decision support
Background Healthcare organizations, compendia, and drug knowledgebase vendors use
varying methods to evaluate and synthesize evidence on drug–drug interactions (DDIs). This …
varying methods to evaluate and synthesize evidence on drug–drug interactions (DDIs). This …
Alcoholism: the dissection for endophenotypes
LM Hines, L Ray, K Hutchison…�- Dialogues in clinical�…, 2005 - Taylor & Francis
Alcohol dependence (alcoholism) is a complex disorder attributed to the interaction of
genetic and environmental factors that form a collage of “disease” predisposition, which is not …
genetic and environmental factors that form a collage of “disease” predisposition, which is not …