FIG. 1. Neogenesis in mouse pancreas. A: The metaplastic ducts seen in the zinc-treated
metallothionen. TGF-transgenic mice have 6% insulin (red, white arrows) cells and some …

Lonidamine (LND) was initially introduced as an antispermatogenic agent. It was later found
to have anticancer activity sensitizing tumors to chemo-, radio-, and photodynamic-therapy …

Melanin is a biological pigment formed by indoles and phenolic compounds. It is widely
found in living organisms and has a variety of unique properties. Due to its diverse …

Chimeric antigen receptors (CARs) redirect T cell cytotoxicity against cancer cells, providing
a promising approach to cancer immunotherapy. Despite extensive clinical use, the …

Seawater electrolysis is an efficient method for producing carbon-neutral hydrogen; however,
it is hindered by high energy cost and chlorine evolution reaction. In this study, we report …

Misfolded proteins compromise cellular function and cause disease. How these proteins are
detected and degraded is not well understood. Here we show that PML/TRIM19 and the …

Immune cells function in diverse metabolic environments. Tissues with low glucose and high
lactate concentrations, such as the intestinal tract or ischemic tissues, frequently require …

Dynamic adaptations in synaptic plasticity are critical for learning new motor skills and
maintaining memory throughout life, which rapidly decline with Parkinson's disease (PD). …

In December 2019, the 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
emerged in China and now has spread in many countries. Pregnant women are …

Agricultural subsidies lead to changes in the use of chemical fertilizer by farmers. Using data
from a household survey conducted annually by the Rural Economy Research Center of …