Glucocorticoid and mineralocorticoid receptors in the brain: a transcriptional perspective
ASCAM Koning, JC Buurstede…�- Journal of the�…, 2019 - academic.oup.com
Adrenal glucocorticoid hormones are crucial for maintenance of homeostasis and adaptation
to stress. They act via the mineralocorticoid receptors (MRs) and glucocorticoid receptors (…
to stress. They act via the mineralocorticoid receptors (MRs) and glucocorticoid receptors (…
[HTML][HTML] Corticosteroid action in the brain: the potential of selective receptor modulation
EMG Viho, JC Buurstede, A Mahfouz, LL Koorneef…�- …, 2019 - karger.com
Glucocorticoid hormones have important effects on brain function in the context of acute and
chronic stress. Many of these are mediated by the glucocorticoid receptor (GR). GR has …
chronic stress. Many of these are mediated by the glucocorticoid receptor (GR). GR has …
An emerging role for microglia in stress‐effects on memory
J Sanguino‐G�mez, JC Buurstede…�- European Journal of�…, 2022 - Wiley Online Library
Stressful experiences evoke, among others, a rapid increase in brain (nor)epinephrine (NE)
levels and a slower increase in glucocorticoid hormones (GCs) in the brain. Microglia are …
levels and a slower increase in glucocorticoid hormones (GCs) in the brain. Microglia are …
Hippocampal glucocorticoid target genes associated with enhancement of memory consolidation
JC Buurstede, LTCM van Weert…�- European Journal of�…, 2022 - Wiley Online Library
Glucocorticoids enhance memory consolidation of emotionally arousing events via largely
unknown molecular mechanisms. This glucocorticoid effect on the consolidation process also …
unknown molecular mechanisms. This glucocorticoid effect on the consolidation process also …
NeuroD factors discriminate mineralocorticoid from glucocorticoid receptor DNA binding in the male rat brain
LTCM van Weert, JC Buurstede, A Mahfouz…�- …, 2017 - academic.oup.com
In the limbic brain, mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) both
function as receptors for the naturally occurring glucocorticoids (corticosterone/cortisol) but …
function as receptors for the naturally occurring glucocorticoids (corticosterone/cortisol) but …
Cell type specificity of glucocorticoid signaling in the adult mouse hippocampus
EMG Viho, JC Buurstede, JB Berkhout…�- Journal of�…, 2022 - Wiley Online Library
Glucocorticoid stress hormones are powerful modulators of brain function and can affect
mood and cognitive processes. The hippocampus is a prominent glucocorticoid target and …
mood and cognitive processes. The hippocampus is a prominent glucocorticoid target and …
[HTML][HTML] Androgens modulate glucocorticoid receptor activity in adipose tissue and liver
…, M Nixon, JC Buurstede…�- Journal of�…, 2019 - joe.bioscientifica.com
Glucocorticoid signaling is context dependent, and in certain scenarios, glucocorticoid
receptors (GRs) are able to engage with other members of the nuclear receptor subfamily. …
receptors (GRs) are able to engage with other members of the nuclear receptor subfamily. …
[HTML][HTML] Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation
JC Buurstede, EHL Umeoka, MS da Silva…�- …, 2022 - Elsevier
Glucocorticoids regulate memory consolidation, facilitating long-term storage of relevant
information to adequately respond to future stressors in similar conditions. This effect of …
information to adequately respond to future stressors in similar conditions. This effect of …
Transcriptional glucocorticoid effects in the brain: Finding the relevant target genes
OC Meijer, JC Buurstede, EMG Viho…�- Journal of�…, 2023 - Wiley Online Library
Glucocorticoids are powerful modulators of brain function. They act via mineralocorticoid and
glucocorticoid receptors (MR and GR). These are best understood as transcription factors. …
glucocorticoid receptors (MR and GR). These are best understood as transcription factors. …
Identification of mineralocorticoid receptor target genes in the mouse hippocampus
LTCM van Weert, JC Buurstede…�- Journal of�…, 2019 - Wiley Online Library
Brain mineralocorticoid receptors ( MR s) and glucocorticoid receptors ( GR s) respond to the
same glucocorticoid hormones but can have differential effects on cellular function. Several …
same glucocorticoid hormones but can have differential effects on cellular function. Several …