Diallyl sulfide as a potential dietary agent to reduce TNF‐α‐and histamine‐induced proinflammatory responses in A 7r5 cells

CY Ho, CJ Weng, JJ Jhang, YT Cheng…�- Molecular nutrition &�…, 2014 - Wiley Online Library
Scope Oxidative stress‐aggravated chronic inflammatory diseases of the airway are well
documented; hence, treatment with antioxidants to ameliorate oxidative stress might be an
effective strategy to reduce airway complications. The aim of this study was to investigate the
effect and molecular mechanism of diallyl sulfide (DAS), which is a natural organosulfuric
compound found in garlic, on the inhibition of tumor necrosis factor‐alpha (TNF‐α)‐or
histamine‐induced inflammation in rat aortic smooth muscle A 7r5 cells. Methods and results�…

Diallyl sulfide as a potential dietary agent to reduce TNF-α-and histamine-induced proinflammatory responses in A7r5 cells.

HCY Ho ChengYing, WCJ Weng ChiaJui… - 2014 - cabidigitallibrary.org
Scope: Oxidative stress-aggravated chronic inflammatory diseases of the airway are well
documented; hence, treatment with antioxidants to ameliorate oxidative stress might be an
effective strategy to reduce airway complications. The aim of this study was to investigate the
effect and molecular mechanism of diallyl sulfide (DAS), which is a natural organosulfuric
compound found in garlic, on the inhibition of tumor necrosis factor-alpha (TNF-α)-or
histamine-induced inflammation in rat aortic smooth muscle A7r5 cells. Methods and results�…
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