Recently, a complex regulatory network that governs iron traffic has emerged, and points to
hepcidin as a major evolutionary conserved regulator of iron distribution [1, 2]. This small …

Afonso J, Reis F–Dexmedetomidine: Current Role in Anesthesia and Intensive Care.
Background and objectives: To update and review the application of dexmedetomidine in …

Diabetes mellitus has emerged as one of the main alarms to human health in the 21st
century. Pronounced changes in the human environment, behavior and lifestyle have …

The human intestine contains an intricate ecological community of dwelling bacteria, referred
as gut microbiota (GM), which plays a pivotal role in host homeostasis. Multiple factors …

The purpose of this paper is to evaluate the chronic effect of sitagliptin on metabolic profile,
inflammation, and redox status in the Zucker Diabetic Fatty (ZDF) rat, an animal model of …

This study was performed to assess the effect of chronic low‐dose sitagliptin, a dipeptidyl
peptidase 4 inhibitor, on metabolic profile and on renal lesions aggravation in a rat model of …

Over the last 30 years the combination of both a sedentary lifestyle and excessive food
availability has led to a significant increase in the prevalence of obesity and aggravation of rates …

This study aimed to evaluate the efficacy of sitagliptin, a dipeptidyl peptidase IV (DPP‐IV)
inhibitor, in preventing the deleterious effects of diabetes on the kidney in an animal model of …

The increased prevalence of type 2 diabetes mellitus (T2DM) and life expectancy of diabetic
patients fosters the worldwide prevalence of retinopathy and nephropathy, two major …

Incretin‐based therapies, the most recent therapeutic options for type 2 diabetes mellitus (T2DM)
management, can modify various elements of the disease, including hypersecretion of …