Many patients with chest pain undergoing coronary angiography do not show significant
obstructive coronary lesions. A substantial proportion of these patients have abnormalities in …

Atherosclerosis is a chronic inflammatory disease, in which the immune system has a prominent
role in its development and progression. Inflammation-induced endothelial dysfunction …

Epidemiological studies have shown that a substantial proportion of acute coronary events
occur in individuals who lack the traditional high-risk cardiovascular (CV) profile. Mental …

Strategies to prevent acute coronary and cerebrovascular events are based on accurate
identification of patients at increased cardiovascular (CV) risk who may benefit from intensive …

Objectives To determine whether there is a relation between statin utilisation and coronary
heart disease (CHD) mortality in populations with different levels of coronary risk, and …

Aims To investigate and compare changes in the rates of ischaemic heart disease (IHD)
incidence and mortality between 1990 and 2019 in 20 high-income Western European …

Endothelial dysfunction is one of the earliest manifestations of atherosclerosis, contributing
to its development and progression. Mental stress induces endothelial dysfunction through …

Background and Aim Left ventricular ( LV ) segmental dyssynchrony is common in patients
with heart failure or myocardial activation abnormalities and is associated with increased …

Identifying patients at increased risk of coronary artery disease, before the atherosclerotic
complications become clinically evident, is the aim of cardiovascular prevention. Imaging …

Risk stratification of cardiovascular death and treatment strategies in patients with heart
failure (HF), the optimal timing for valve replacement, and the selection of patients for …