The analysis of spatial learning and memory in rodents is commonly used to investigate the
mechanisms underlying certain forms of human cognition and to model their dysfunction in …

Traumatic events can engender persistent excessive fear responses to trauma reminders
that may return even after successful treatment. Extinction, the laboratory analog of behavior …

The balance between excitation and inhibition controls fundamental aspects of the hippocampal
function. Here, we report an increase in the ratio of inhibitory to excitatory neurons in the …

Adult zebrafish, in contrast to mammals, regrow axons descending from the brainstem after
spinal cord transection. L1.1, a homolog of the mammalian recognition molecule L1, is …

The extracellular matrix glycoprotein tenascin-C (TN-C) has been suggested to play important
functional roles during neural development, axonal regeneration, and synaptic plasticity. …

Introduction Neurofibrillary tangles (NFT) composed of Tau are hallmarks of neurodegeneration
in Alzheimer disease. Transgenic mice expressing full-length pro-aggregant human Tau …

Atypical brain connectivity is a major contributor to the pathophysiology of neurodevelopmental
disorders (NDDs) including autism spectrum disorders (ASDs). TAOK2 is one of several …

The nervous system is vulnerable to perturbations during specific developmental periods.
Insults during such susceptible time windows can have long-term consequences, including the …

Phosphorylated creatine (Cr) serves as an energy buffer for ATP replenishment in organs
with highly fluctuating energy demand. The central role of Cr in the brain and muscle is …

We investigated the behavior of mice deficient for the extracellular matrix (ECM) glycoprotein
tenascin-R (TN-R) in comparison to their wild-type (WT) littermates. A longitudinal study …