Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion
…, H Hemmati, MK Delmedico, DM Lambert…�- The Journal of cell�…, 2000 - rupress.org
Many viral fusion proteins exhibit a six-helix bundle as a core structure. HIV Env–induced
fusion was studied to resolve whether membrane merger was due to the transition into the …
fusion was studied to resolve whether membrane merger was due to the transition into the …
Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry
…, GA Cloud, JY Lee, L Alldredge, E Hunter, D Lambert…�- Nature medicine, 1998 - nature.com
T-20, a synthetic peptide corresponding to a region of the transmembrane subunit of the HIV-1
envelope protein, blocks cell fusion and viral entry at concentrations of less than 2 ng/ml …
envelope protein, blocks cell fusion and viral entry at concentrations of less than 2 ng/ml …
Binding of soluble CD4 proteins to human immunodeficiency virus type 1 and infected cells induces release of envelope glycoprotein gp120.
…, H Ellens, RW Sweet, DM Lambert…�- Proceedings of the�…, 1991 - National Acad Sciences
Human immunodeficiency virus (HIV) infects cells after binding of the viral envelope glycoprotein
gp120 to the cell surface recognition marker CD4. gp120 is noncovalently associated …
gp120 to the cell surface recognition marker CD4. gp120 is noncovalently associated …
Synthesis and anti-HSV activity of a-ring-deleted mappicine ketone analog
…, S Barney, R Wittrock, DM Lambert…�- The Journal of�…, 1994 - ACS Publications
MPK has been identified as an antiviral lead compound with selective activity against
herpesviruses HSV-1, HSV-2, and human cytomegalovirus (HCMV) with PRso’s of 2.9, 0.5 and …
herpesviruses HSV-1, HSV-2, and human cytomegalovirus (HCMV) with PRso’s of 2.9, 0.5 and …
Inhibition of HIV-1 protease in infected T-lymphocytes by synthetic peptide analogues
TD Meek, DM Lambert, GB Dreyer, TJ Carr…�- Nature, 1990 - nature.com
THE gag and pol genes of the human immunodeficiency virus type 1 (HIV-1) (ref. 1) are
translated as two polyproteins, Pr55 gag and Prl60 gag-pol (refs 2-6), which are subsequently …
translated as two polyproteins, Pr55 gag and Prl60 gag-pol (refs 2-6), which are subsequently …
[CITATION][C] Distribution and fate of energetics on DoD test and training ranges: Interim Report 5
…, SL Yost, KL Bjella, L Trepanier, TE Berry, DJ Lambert… - 2005 - erdc-library.erdc.dren.mil
The potential for generation of environmental contamination in the form of residual munitions
constituents during live-fire training activities on military ranges is a significant concern. The …
constituents during live-fire training activities on military ranges is a significant concern. The …
Role of oligosaccharides in the structure and function of respiratory syncytial virus glycoproteins
DM Lambert�- Virology, 1988 - Elsevier
The contribution of oligosaccharides to the structural and functional make-up of respiratory
syncytial (RS) virus G and F proteins was investigated by observing the effects of various …
syncytial (RS) virus G and F proteins was investigated by observing the effects of various …
Association of telomere length with risk of complications in adult spinal deformity surgery: a pilot study of 43 patients
OBJECTIVE Risk stratification is a critical element of surgical planning. Early tools were fairly
crude, while newer instruments incorporate disease-specific elements and markers of frailty…
crude, while newer instruments incorporate disease-specific elements and markers of frailty…
Motor cognition: The role of sentience in perception and action
…, Y Li, CY Wong, D Lambert�- Kinesiology�…, 2020 - journals.humankinetics.com
The function of the conscious field remains mysterious from a scientific point of view. This
article reviews theoretical approaches (passive frame theory and ideomotor approaches) that …
article reviews theoretical approaches (passive frame theory and ideomotor approaches) that …
Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected�…
GB Dreyer, DM Lambert, TD Meek, TJ Carr…�- Biochemistry, 1992 - ACS Publications
Revised Manuscript Received March 24, 1992 abstract: Analogues of peptides ranging in size
from three to six amino acids and containing the hy-droxyethylene dipeptide isosteres Phe'…
from three to six amino acids and containing the hy-droxyethylene dipeptide isosteres Phe'…