User profiles for Dejan B. Budimirovic
 | Dejan B. Budimirovic, MDKennedy Krieger Institute Verified email at kennedykrieger.org Cited by 1839 |
[HTML][HTML] Updated report on tools to measure outcomes of clinical trials in fragile X syndrome
DB Budimirovic, E Berry-Kravis, CA Erickson…�- Journal of�…, 2017 - Springer
Objective Fragile X syndrome (FXS) has been the neurodevelopmental disorder with the most
active translation of preclinical breakthroughs into clinical trials. This process has led to a …
active translation of preclinical breakthroughs into clinical trials. This process has led to a …
What can we learn about autism from studying fragile X syndrome?
DB Budimirovic, WE Kaufmann�- Developmental neuroscience, 2011 - karger.com
Despite early controversy, it is now accepted that a substantial proportion of children with
fragile X syndrome (FXS) meets diagnostic criteria for autism spectrum disorder (ASD). This …
fragile X syndrome (FXS) meets diagnostic criteria for autism spectrum disorder (ASD). This …
[HTML][HTML] A Genotype-Phenotype Study of High-Resolution FMR1 Nucleic Acid and Protein Analyses in Fragile X Patients with Neurobehavioral Assessments
DB Budimirovic, A Schlageter, S Filipovic-Sadic…�- Brain sciences, 2020 - mdpi.com
Fragile X syndrome (FXS) is caused by silencing of the FMR1 gene, which encodes a
protein with a critical role in synaptic plasticity. The molecular abnormality underlying FMR1 …
protein with a critical role in synaptic plasticity. The molecular abnormality underlying FMR1 …
Autism spectrum disorder in fragile X syndrome: cooccurring conditions and current treatment
BACKGROUND AND OBJECTIVE: Individuals with fragile X syndrome (FXS) are frequently
codiagnosed with autism spectrum disorder (ASD). Most of our current knowledge about …
codiagnosed with autism spectrum disorder (ASD). Most of our current knowledge about …
Autism spectrum disorder in Fragile X syndrome: differential contribution of adaptive socialization and social withdrawal
DB Budimirovic, I Bukelis, C Cox…�- American journal of�…, 2006 - Wiley Online Library
The present study extends our previous work on characterizing the profile of social behavior
abnormalities in boys with Fragile X (FraX) and autism spectrum disorder (ASD) using …
abnormalities in boys with Fragile X (FraX) and autism spectrum disorder (ASD) using …
Sleep problems in fragile X syndrome: Cross‐sectional analysis of a large clinic‐based cohort
DB Budimirovic, DD Protic…�- American Journal of�…, 2022 - Wiley Online Library
Fragile X syndrome (FXS), the leading cause of inherited intellectual disability and autism
spectrum disorder, is associated with multiple neurobehavioral abnormalities including sleep …
spectrum disorder, is associated with multiple neurobehavioral abnormalities including sleep …
[HTML][HTML] Fragile X syndrome: from molecular aspect to clinical treatment
…, F Mitrovic, RJ Hagerman, DB Budimirovic�- International journal of�…, 2022 - mdpi.com
… All the above funding has been directed to Kennedy Krieger Institute/the Johns Hopkins
Medical Institutions; Dejan B. Budimirovic receives no personal funds and the Institute has no …
Medical Institutions; Dejan B. Budimirovic receives no personal funds and the Institute has no …
[HTML][HTML] Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on FMR1 Premutation
The premutation of the fragile X messenger ribonucleoprotein 1 (FMR1) gene is characterized
by an expansion of the CGG trinucleotide repeats (55 to 200 CGGs) in the 5’ untranslated …
by an expansion of the CGG trinucleotide repeats (55 to 200 CGGs) in the 5’ untranslated …
Mosaic FMR1 deletion causes fragile X syndrome and can lead to molecular misdiagnosis: A case report and review of the literature
B Coffee, M Ikeda, DB Budimirovic…�- American Journal of�…, 2008 - Wiley Online Library
The most common cause of fragile X syndrome is expansion of a CGG trinucleotide repeat
in the 5′UTR of FMR1. This expansion leads to transcriptional silencing of the gene. …
in the 5′UTR of FMR1. This expansion leads to transcriptional silencing of the gene. …
[HTML][HTML] Cerebral expression of metabotropic glutamate receptor subtype 5 in idiopathic autism spectrum disorder and fragile X syndrome: a pilot study
Multiple lines of evidence suggest that dysfunction of the metabotropic glutamate receptor
subtype 5 (mGluR 5 ) plays a role in the pathogenesis of autism spectrum disorder (ASD). Yet …
subtype 5 (mGluR 5 ) plays a role in the pathogenesis of autism spectrum disorder (ASD). Yet …