With osteoarthritis being the most common degenerative disease in pet animals, a very broad
panel of natural health products is available on the market for its management. The aim of …

Objectives Feline osteoarthritis causes pain and disability. Detection and measurement is
challenging, relying heavily on owner report. This study describes refinement of the Montreal …

Validating animal pain models is crucial to enhancing translational research and response
to pharmacological treatment. This study investigated the effects of a calibrated slight …

Background Lack of validity in osteoarthritis pain models and assessment methods is suspected.
Our goal was to 1) assess the repeatability and reproducibility of measurement and the …

Purpose Several observational studies suggest that estrogens could bias pain perception.
To evaluate the influence of estrogenic impregnation on pain expression, a prospective, …

Quantitative sensory testing (QST) is a psychophysical test used to quantify somatosensory
sensation under normal or pathological conditions including osteoarthritis (OA). Objective …

Abstract Evaluation of nociceptive sensitisation in canine osteoarthritis studies has been
poorly reported, or even related to other clinical symptoms. In 16 dogs, peak vertical force (PVF)…

Purpose: Because oxytocin (OT) is potentially useful in cardiovascular therapy but has
hormonal roles on the cardiovascular and renal systems, we characterized its pharmacokinetic (…

Background and aims Characterising the temporal evolution of changes observed in pain
functional assessment, spinal neuropeptides and cartilage lesions of the joint after chemical …

The effects of oxytocin (OT) on cardiovascular endpoints were assessed in a myocardial
infarct (MI) model. OT (10 ng� kg− 1� hour− 1) or saline infusion was initiated at reperfusion (D0) …