Accumulating data indicates a link between a pro-inflammatory status and occurrence of
chronic disease-related fatigue. The questions are whether the observed inflammatory profile …

Aging is accompanied by a progressive decline of muscle mass and strength and also higher
levels of circulating cytokines such as growth differentiation factor 15 (GDF15). Studies …

Age-related changes in body composition reflect an increased risk for disease as well as
disability. Bioimpedance analysis is a safe and inexpensive bed side method to measure body …

Western-style obesity-promoting diets are associated with increased inflammation, higher
disease incidence and mortality. In contrast, plant-based diets (PBDs), which incorporate large …

Background & aims Fibroblast growth factor 21 (FGF21) plays a pivotal role in glucose and
lipid metabolism and has been proposed as a longevity hormone. However, elevated plasma …

Background It remains unknown why adiponectin levels are associated with poor physical
functioning, skeletal muscle mass and increased mortality in older populations. Methods In …

Background Frailty development is partly dependent on multiple factors like low levels of
nutrients and high levels of oxidative stress (OS) and inflammation potentially leading to a …

Understanding the intricate mechanisms governing the cellular response to resistance
exercise is paramount for promoting healthy aging. This narrative review explored the age-related …

Background Fatigue is a complex syndrome associated with exhaustion not relieved by sleep.
It occurs frequently in older adults in the context of chronic disease and is associated with …

Background: Inflammaging is considered to drive loss of muscle function. Omega-3 fatty acids
exhibit anti-inflammatory properties. Therefore, we examined the effects of eight weeks of …