Aims: Metformin improves glucose regulation through various mechanisms in the periphery.
Our previous study revealed that oral intake of metformin activates several brain regions, …

Introduction Metformin has shown cardioprotective and neuroprotective effects in cardiac arrest
and ischemia-reperfusion injury animal models. Therefore, this study aimed to determine …

Aims We investigated whether modulation of white adipose tissue (WAT) vasculature regulates
rebound weight gain (RWG) after caloric restriction (CR) in mice fed a high-fat diet (HFD). …

Objective Adipose tissue (AT) expansion requires AT remodeling, which depends on AT
angiogenesis. Modulation of AT angiogenesis could have therapeutic promise for the treatment …

Ischemia-modified albumin (IMA) is produced during ischemia and reactive oxygen species
production. This study aimed to evaluate the association between IMA and mortality in a …

Survival benefits of prehospital advanced airway and epinephrine in out-of-hospital cardiac
arrest (OHCA) patients are controversial, but few studies evaluated this together. This study …

Muscle mass depletion is associated with mortality and morbidity in various conditions
including sepsis. However, few studies have evaluated muscle mass using point-of-care …

Sex differences in the in-hospital management of sepsis exist. Previous studies either included
patients with sepsis that was defined using previous definitions of sepsis or evaluated the …

Metformin reduces body weight by decreasing food intake in humans and animals. However,
the brain regions involved in metformin-induced anorexia remain unclear. Therefore, we …

Vascular reactivity of adipose tissue (AT) is hypothesized to play an important role in the
development of obesity. However, the exact role of vascular reactivity in the development of …