Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology

…, C Tian, JD Hoffman, Q Helmer, A Tillander…�- Nature�…, 2017 - nature.com
Asthma, hay fever (or allergic rhinitis) and eczema (or atopic dermatitis) often coexist in the
same individuals 1 , partly because of a shared genetic origin 2 , 3 , 4 . To identify shared risk …

Vagotomy and Parkinson disease: A Swedish register–based matched-cohort study

B Liu, F Fang, NL Pedersen, A Tillander…�- Neurology, 2017 - AAN Enterprises
Objective: To examine whether vagotomy decreases the risk of Parkinson disease (PD).
Methods: Using data from nationwide Swedish registers, we conducted a matched-cohort study …

Bidirectional relationship between eating disorders and autoimmune diseases

…, C H�bel, LM Thornton, A Tillander…�- Journal of Child�…, 2019 - Wiley Online Library
Background Immune system dysfunction may be associated with eating disorders ( ED ) and
could have implications for detection, risk assessment, and treatment of both autoimmune …

Relative immaturity and ADHD: findings from nationwide registers, parent‐and self‐reports

L Halldner, A Tillander, C Lundholm…�- Journal of child�…, 2014 - Wiley Online Library
Background We addressed if immaturity relative to peers reflected in birth month increases
the likelihood of ADHD diagnosis and treatment. Methods We linked nationwide Patient and …

Covariance structure approximation via gLasso in high-dimensional supervised classification

T Pavlenko, A Bj�rkstr�m, A Tillander�- Journal of Applied Statistics, 2012 - Taylor & Francis
Recent work has shown that the Lasso-based regularization is very useful for estimating the
high-dimensional inverse covariance matrix. A particularly useful scheme is based on …

Body mass index in relation to serum prostate‐specific antigen levels and prostate cancer risk

SE Bonn, A Sj�lander, A Tillander…�- …�journal of cancer, 2016 - Wiley Online Library
High Body mass index (BMI) has been directly associated with risk of aggressive or fatal
prostate cancer. One possible explanation may be an effect of BMI on serum levels of prostate‐…

Telomere length shortening and Alzheimer disease—a Mendelian randomization study

Y Zhan, CI Song, R Karlsson, A Tillander…�- JAMA�…, 2015 - jamanetwork.com
Methods| We used 7 lead single-nucleotide polymorphisms (SNPs) identified to be of
genome-wide significance4 as IVs for TL and extracted the final estimates of these SNPs on AD …

Exploring the causal pathway from telomere length to coronary heart disease: a network Mendelian randomization study

Y Zhan, IK Karlsson, R Karlsson, A Tillander…�- Circulation�…, 2017 - Am Heart Assoc
Rationale: Observational studies have found shorter leukocyte telomere length (TL) to be a
risk factor for coronary heart disease (CHD), and recently the association was suggested to …

Effect of data discretization on the classification accuracy in a high‐dimensional framework

A Tillander�- International Journal of Intelligent Systems, 2012 - Wiley Online Library
We investigate discretization of continuous variables for classification problems in a high‐
dimensional framework. As the goal of classification is to correctly predict a class membership …

Occupational stress and risk for Parkinson's disease: a nationwide cohort study

J Sieurin, R Andel, A Tillander, EG Valdes…�- Movement�…, 2018 - Wiley Online Library
Background: Stress has been suggested as a contributing factor in the etiology of Parkinson's
Disease (PD), but epidemiological evidence is sparse. Objective: The objective of this …