Basic local alignment search tool
A new approach to rapid sequence comparison, basic local alignment search tool (BLAST),
directly approximates alignments that optimize a measure of local similarity, the maximal
segment pair (MSP) score. Recent mathematical results on the stochastic properties of MSP
scores allow an analysis of the performance of this method as well as the statistical
significance of alignments it generates. The basic algorithm is simple and robust; it can be
implemented in a number of ways and applied in a variety of contexts including straight�…
directly approximates alignments that optimize a measure of local similarity, the maximal
segment pair (MSP) score. Recent mathematical results on the stochastic properties of MSP
scores allow an analysis of the performance of this method as well as the statistical
significance of alignments it generates. The basic algorithm is simple and robust; it can be
implemented in a number of ways and applied in a variety of contexts including straight�…
[CITATION][C] Basic local alignment search tool
A Sf�- J Mol Biol, 1990 - cir.nii.ac.jp
… ALTSCHUL SF … J Mol Biol J Mol Biol 215 403-410, 1990 …
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