Carbendazim (methyl 2-benzimidazolecarbamate) is widely used as a systemic fungicide in
human food production and appears to act on fungal tubulin. However, it also inhibits�…

Microtubules are major constituents of the cytoskeleton which display dynamic properties.
They exhibit dynamic instability which is defined as the stochastic switching between�…

Tetraploidy can arise from various mitotic or cleavage defects in mammalian cells, and
inheritance of multiple centrosomes induces aneuploidy when tetraploid cells continue to�…

Abstract NAP (Asn-Ala-Pro-Val-Ser-Ile-Pro-Gln) is a neuroprotective peptide that shows
cognitive protection in patients with amnestic mild cognitive impairment, a precursor to�…

The microtubule binding protein tau is strongly implicated in multiple neurodegenerative
disorders, including frontotemporal dementia and parkinsonism linked to chromosome 17�…

We previously identified TD-60 (RCC2) as a mitotic centromere-associated protein that is
necessary for proper completion of mitosis. We now report that TD-60 is an essential�…

Microtubules are cylindrical, cytoskeletal protein polymers found in all eukaryotic cells. They
perform a plethora of functions associated with cellular structure, organization, and�…

Frontotemporal Dementia with Parkinsonism linked to chromosome‐17 (FTDP‐17) is a class
of inherited neurodegenerative diseases caused by mutations in the tau gene. Tau protein is�…

Abstract 1407 Carbendazim (CBZ) is a widely used systemic fungicide belonging to the
class of benzimidazole derivatives that is undergoing development for cancer�…

The mitotic spindle consists of a highly organized fusiform array of microtubules which
functions to precisely segregate chromosomes during cell division. Both motor and non�…