Coherent anti-Stokes Raman scattering microscopy: chemical imaging for biology and medicine
Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free imaging
technique that is capable of real-time, nonperturbative examination of living cells and�…
technique that is capable of real-time, nonperturbative examination of living cells and�…
Optical studies of single molecules at room temperature
XS Xie, JK Trautman�- Annual review of physical chemistry, 1998 - annualreviews.org
▪ Abstract Recent developments in optical studies of single molecules at room temperature
are reviewed, with an emphasis on the underlying principles and the potential of single�…
are reviewed, with an emphasis on the underlying principles and the potential of single�…
Vibrational spectroscopic imaging of living systems: An emerging platform for biology and medicine
BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from�…
molecular vibration spectra in living cells and tissues. However, the transition from�…
[HTML][HTML] Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies
Abstract The SARS-CoV-2 B. 1.1. 529 (Omicron) variant contains 15 mutations of the
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies�…
receptor-binding domain (RBD). How Omicron evades RBD-targeted neutralizing antibodies�…
[HTML][HTML] BA. 2.12. 1, BA. 4 and BA. 5 escape antibodies elicited by Omicron infection
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages BA.
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage 1. The receptor�…
2.12. 1, BA. 4 and BA. 5 exhibit higher transmissibility than the BA. 2 lineage 1. The receptor�…
Label-free biomedical imaging with high sensitivity by stimulated Raman scattering microscopy
Label-free chemical contrast is highly desirable in biomedical imaging. Spontaneous
Raman microscopy provides specific vibrational signatures of chemical bonds, but is often�…
Raman microscopy provides specific vibrational signatures of chemical bonds, but is often�…
Quantifying E. coli Proteome and Transcriptome with Single-Molecule Sensitivity in Single Cells
Protein and messenger RNA (mRNA) copy numbers vary from cell to cell in isogenic
bacterial populations. However, these molecules often exist in low copy numbers and are�…
bacterial populations. However, these molecules often exist in low copy numbers and are�…
[HTML][HTML] Imprinted SARS-CoV-2 humoral immunity induces convergent Omicron RBD evolution
Continuous evolution of Omicron has led to a rapid and simultaneous emergence of
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent�…
numerous variants that display growth advantages over BA. 5 (ref.). Despite their divergent�…
Three-dimensional vibrational imaging by coherent anti-Stokes Raman scattering
A Zumbusch, GR Holtom, XS Xie�- Physical review letters, 1999 - APS
A multiphoton microscopy based on coherent anti-Stokes Raman scattering is accomplished
with near-infrared ultrashort laser pulses. We demonstrate vibrational imaging of chemical�…
with near-infrared ultrashort laser pulses. We demonstrate vibrational imaging of chemical�…
Single-molecule enzymatic dynamics
Enzymatic turnovers of single cholesterol oxidase molecules were observed in real time by
monitoring the emission from the enzyme's fluorescent active site, flavin adenine�…
monitoring the emission from the enzyme's fluorescent active site, flavin adenine�…