User profiles for "author:Wu AR"

Angela R Wu

- Verified email at ust.hk - Cited by 4425

Amy R Wu

- Verified email at queensu.ca - Cited by 593

Single-cell transcriptional analysis

AR Wu, J Wang, AM Streets…�- Annual Review of�…, 2017 - annualreviews.org
Despite being a relatively recent technological development, single-cell transcriptional
analysis through high-throughput sequencing has already been used in hundreds of fruitful�…

Reconstructing lineage hierarchies of the distal lung epithelium using single-cell RNA-seq

B Treutlein, DG Brownfield, AR Wu, NF Neff…�- Nature, 2014 - nature.com
The mammalian lung is a highly branched network in which the distal regions of the
bronchial tree transform during development into a densely packed honeycomb of alveolar�…

Quantitative assessment of single-cell RNA-sequencing methods

AR Wu, NF Neff, T Kalisky, P Dalerba, B Treutlein…�- Nature�…, 2014 - nature.com
Interest in single-cell whole-transcriptome analysis is growing rapidly, especially for profiling
rare or heterogeneous populations of cells. We compared commercially available single-cell�…

[HTML][HTML] Single mammalian cells compensate for differences in cellular volume and DNA copy number through independent global transcriptional mechanisms

O Padovan-Merhar, GP Nair, AG Biaesch, A Mayer…�- Molecular cell, 2015 - cell.com
Individual mammalian cells exhibit large variability in cellular volume, even with the same
absolute DNA content, and so must compensate for differences in DNA concentration in�…

[HTML][HTML] Vascularized human brain organoid on-chip

SY Tan, X Feng, LKW Cheng, AR Wu�- Lab on a Chip, 2023 - pubs.rsc.org
Modelling the human brain in vitro has been extremely challenging due to the brain's
intricate cellular composition and specific structural architecture. The recent emergence of�…

Microfluidic single-cell analysis—Toward integration and total on-chip analysis

CW Fung, SN Chan, AR Wu�- Biomicrofluidics, 2020 - pubs.aip.org
Various types of single-cell analyses are now extensively used to answer many biological
questions, and with this growth in popularity, potential drawbacks to these methods are also�…

Construction of a 3D whole organism spatial atlas by joint modelling of multiple slices with deep neural networks

G Wang, J Zhao, Y Yan, Y Wang, AR Wu…�- Nature Machine�…, 2023 - nature.com
Spatial transcriptomics (ST) technologies are revolutionizing the way to explore the spatial
architecture of tissues. Currently, ST data analysis is often restricted to a single two�…

scONE-seq: A single-cell multi-omics method enables simultaneous dissection of phenotype and genotype heterogeneity from frozen tumors

L Yu, X Wang, Q Mu, SST Tam, DSC Loi, AKY Chan…�- Science�…, 2023 - science.org
Single-cell multi-omics can provide a unique perspective on tumor cellular heterogeneity.
Most previous single-cell whole-genome RNA sequencing (scWGS-RNA-seq) methods�…

[HTML][HTML] Integrating spatial and single-cell transcriptomics data using deep generative models with SpatialScope

X Wan, J Xiao, SST Tam, M Cai, R Sugimura…�- Nature�…, 2023 - nature.com
The rapid emergence of spatial transcriptomics (ST) technologies is revolutionizing our
understanding of tissue spatial architecture and biology. Although current ST methods�…

Symbitron exoskeleton: Design, control, and evaluation of a modular exoskeleton for incomplete and complete spinal cord injured individuals

C Meijneke, G Van Oort, V Sluiter…�- …�on Neural Systems�…, 2021 - ieeexplore.ieee.org
In this paper, we present the design, control, and preliminary evaluation of the Symbitron
exoskeleton, a lower limb modular exoskeleton developed for people with a spinal cord�…