User profiles for "author:Werts A"

Adam Werts

Zoetis
Verified email at zoetis.com
Cited by 1401

The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2

AL Cathcart, C Havenar-Daughton, FA Lempp, D Ma…�- biorxiv, 2021 - biorxiv.org
ABSTRACT VIR-7831 and VIR-7832 are dual action monoclonal antibodies (mAbs)
targeting the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS�…

[HTML][HTML] A novel role for necroptosis in the pathogenesis of necrotizing enterocolitis

AD Werts, WB Fulton, MR Ladd, A Saad-Eldin…�- Cellular and molecular�…, 2020 - Elsevier
Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and�…

Triggering a cell shape change by exploiting preexisting actomyosin contractions

M Roh-Johnson, G Shemer, CD Higgins, JH McClellan…�- Science, 2012 - science.org
Apical constriction changes cell shapes, driving critical morphogenetic events, including
gastrulation in diverse organisms and neural tube closure in vertebrates. Apical constriction�…

Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

SN Langel, S Johnson, CI Martinez…�- Science Translational�…, 2022 - science.org
Transmission-blocking strategies that slow the spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and protect against coronavirus disease 2019 (COVID-19) are�…

The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4�…

CP Sodhi, P Wipf, Y Yamaguchi, WB Fulton…�- Pediatric�…, 2021 - nature.com
Background Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor
4 (TLR4) signaling in the intestinal epithelium. Breast milk is rich in non-digestible�…

[HTML][HTML] Tissue engineering for the treatment of short bowel syndrome in children

LY Martin, MR Ladd, A Werts, CP Sodhi, JC March…�- Pediatric�…, 2018 - nature.com
Short bowel syndrome is a major cause of morbidity and mortality in children. Despite
decades of experience in the management of short bowel syndrome, current therapy is�…

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

CF Gao, K Furge, J Koeman…�- Proceedings of the�…, 2007 - National Acad Sciences
Chromosome instability and aneuploidy are hallmarks of cancer, but it is not clear how
changes in the chromosomal content of a cell contribute to the malignant phenotype�…

A dynamic variation of pulmonary ACE2 is required to modulate neutrophilic inflammation in response to Pseudomonas aeruginosa lung infection in mice

CP Sodhi, J Nguyen, Y Yamaguchi…�- The Journal of�…, 2019 - journals.aai.org
Abstract Angiotensin-converting enzyme 2 (ACE2) is a potent negative regulator capable of
restraining overactivation of the renin–angiotensin system, which contributes to exuberant�…

Reframing the study of policy implementation: Lived experience as politics

AB Werts, CA Brewer�- Educational Policy, 2015 - journals.sagepub.com
This policy implementation study examines the experiences of four elementary school
principals using photomethods. We employ Ranci�re and Merleau-Ponty's theorizations on�…

Oral vaccination protects against severe acute respiratory syndrome coronavirus 2 in a Syrian hamster challenge model

S Johnson, CI Martinez…�- The Journal of�…, 2022 - academic.oup.com
Background Vaccines that are shelf stable and easy to administer are crucial to improve
vaccine access and reduce severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)�…