We have chosen tumors of the uterine cervix as a model system to identify chromosomal
aberrations that occur during carcinogenesis. A phenotype/genotype correlation was�…

Comparative genomic hybridization was used to screen the DNA extracted from
histologically defined tissue sections from consecutive stages of colorectal carcinogenesis�…

The gist of my hypothesis (.. is) a certain abnormal chromatin constitution. Each process,
which brings about this chromatin constitution, would result in the origin of a malignant�…

Dysplasia is linked to altered tissue architecture. The lesion belongs into the diagnostic field
of human pathology and is highly relevant for the clinical physician, because it breaks the�…

This project was focused on cellular proliferation relative to the onset of endoreplication and
effects of DNA aneuploidy during carcinogenesis in cervical mucosa. Proliferation was�…

Long-standing ulcerative colitis is considered to be a precancerous condition. Therefore, a
practical and reliable method is required for monitoring the progress of the disease�…

In the information systems development, software engineers seek to improve the systems'
functionality and usability, which may require a review of their requirements. Considering a�…

A variety of chromosomal gains and losses has been detected with comparative genomic
hybridization during tumorigenesis in the colon mucosa. The aim of this investigation was to�…

Proliferating cell nuclear antigen (PCNA), nuclear DNA content and mutant p53
overexpression were studied by means of image cytometry and immunohistochemistry�…

With regard to the classification of precancerous lesions, this is the first approach to compare
modes of the cell cycle in benign lesions and neoplasia in oral mucosa. The main objective�…