Small, soluble metabolites not only are essential intermediates in intracellular biochemical
processes, but can also influence neighbouring cells when released into the extracellular�…

RNA sequencing (RNA-Seq) is a powerful tool for transcriptome profiling, but is hampered
by sequence-dependent bias and inaccuracy at low copy numbers intrinsic to exponential�…

Higher-or lower-affinity germinal center (GC) B cells are directed either to plasma cell or GC
recycling, respectively; however, how commitment to the plasma cell fate takes place is�…

Myosin V is a molecular motor that moves cargo along actin filaments. Its two heads, each
attached to a long and relatively stiff neck, move alternately forward in a “hand-over-hand”�…

An essential part of gene expression is the coordination of RNA synthesis and degradation,
which occurs in the same cellular compartment in bacteria. Here, we report a genome‐wide�…

Invariant natural killer T (iNKT) cells are a group of innate-like T lymphocytes that recognize
lipid antigens. They are supposed to be tissue resident and important for systemic and local�…

Bacteria often function as a community, called the microbiota, consisting of many different
bacterial species. The accurate identification of bacterial types and the simultaneous�…

Background Metformin (Met) is the first-line treatment for type 2 diabetes mellitus and plays
an effective role in treating various diseases, such as cardiovascular disease�…

Single-cell whole-transcriptome analysis is the gold standard approach to identifying
molecularly defined cell phenotypes. However, this approach cannot be used for dynamics�…

IL-31 receptor blockade suppresses pruritus of atopic dermatitis. However, cell-type-specific
contributions of IL-31 receptor to itch, its expression mechanism, and the downstream�…