Gene expression is a multistep process that involves the transcription, translation and
turnover of messenger RNAs and proteins. Although it is one of the most fundamental�…

Multiple Arabidopsis thaliana clones from an experimental series of cDNA microarrays are
evaluated in order to identify essential sources of noise in the spotting and hybridization�…

Mark Biggin of the Lawrence Berkeley National Laboratory contacted us, noting that our
mass-spectrometry-based protein copy number estimates are lower than several literature�…

Although tuberculosis remains a substantial global threat, the mechanisms that enable
mycobacterial persistence and replication within the human host are ill defined. This study�…

We study discrete parallel dynamics of a fully connected network of nonlinear elements
interacting via long-range random asymmetric couplings under the influence of external�…

Background The progression of mild cognitive impairment (MCI) to Alzheimer's disease (AD)
dementia can be predicted by cognitive, neuroimaging, and cerebrospinal fluid (CSF)�…

The transition to market-based economic systems in the countries of Central and Eastern
Europe and the former Soviet Union involves fundamental shifts in the allocation of�…

Background A reduced amyloid-β (Aβ) 42/40 peptide ratio in blood plasma represents a
peripheral biomarker of the cerebral amyloid pathology observed in Alzheimer's disease�…

Background The quantification of amyloid-beta (Aβ) peptides in blood plasma as potential
biomarkers of Alzheimer's disease (AD) is hampered by very low Aβ concentrations and the�…

Uncovering cellular responses from heterogeneous genomic data is crucial for molecular
medicine in particular for drug safety. This can be realized by integrating the molecular�…