Regulation of patterning and morphogenesis during embryonic development depends on
tissue-specific signaling by retinoic acid (RA), the active form of Vitamin A (retinol). The first�…

Aneuploidy, referring here to genome contents characterized by abnormal numbers of
chromosomes, has been associated with developmental defects, cancer and adaptive�…

A common landmark of activated genes is the presence of trimethylation on lysine 4 of
histone H3 (H3K4) at promoter regions. Set1/COMPASS was the founding member and is�…

Methylation of histone 3 lysine 4 (H3K4) by yeast Set1-COMPASS requires prior
monoubiquitination of histone H2B. To define whether other residues within the histones are�…

Mice carrying mutations in Wise (Sostdc1) display defects in many aspects of tooth
development, including tooth number, size and cusp pattern. To understand the basis of�…

When San Francisco implemented a new policy to improve graduation rates and college
enrollment, district officials realized their work was only beginning. San Francisco Unified�…

DURING recent years many more cases are being reported of this rare disease complicating
pregnancy and labour. The increased incidence of the combination is due, at least partly, to�…

Patients with benign tumor may more safely wait, especially if their symptoms are not
alarming. One of the authors' patients with a meningioma went through two pregnancies�…