Gene expression is a fundamentally stochastic process, with randomness in transcription
and translation leading to cell-to-cell variations in mRNA and protein levels. This variation�…

This paper examines barriers to the implementation of Industry 4.0 technologies in the
manufacturing sector in the context of both developed and developing economies. A�…

Both the transcription of mRNAs from genes and their subsequent translation into proteins
are inherently stochastic biochemical events, and this randomness can lead to substantial�…

Individual cells in genetically homogeneous populations have been found to express
different numbers of molecules of specific proteins. We investigated the origins of these�…

The phenotypic differences between individual organisms can often be ascribed to
underlying genetic and environmental variation. However, even genetically identical�…

We recently showed that the mammalian genome encodes> 1,000 large intergenic
noncoding (linc) RNAs that are clearly conserved across mammals and, thus, functional�…

Therapies that target signalling molecules that are mutated in cancers can often have
substantial short-term effects, but the emergence of resistant cancer cells is a major barrier�…

We describe a method for imaging individual mRNA molecules in fixed cells by probing
each mRNA species with 48 or more short, singly labeled oligonucleotide probes. This�…

Patterns of dementia are known to fall into dissociated but dispersed brain networks,
suggesting that the disease is transmitted along neuronal pathways rather than by proximity�…

ContextIntimate partner violence against women is a major public health concern. Research
among adults has shown that younger age is a consistent risk factor for experiencing and�…