We demonstrate that the nuclear topological arrangement of chromosome territories (CTs)
has been conserved during primate evolution over a period of about 30 million years�…

OBJECTIVE—Glomerular mesangial expansion and podocyte loss are important early
features of diabetic nephropathy, whereas tubulointerstitial injury and fibrosis are critical for�…

The endoplasmic reticulum (ER) is an important site for protein folding and becomes
“stressed” when its capacity to fold proteins is overwhelmed. In response,“unfolded protein�…

In the kidney, hypoxia contributes to tubulointerstitial fibrosis, but little is known about its
implications for glomerular damage and glomerulosclerosis. Chronic hypoxia was�…

Abstract The revised 2017 European LeukemiaNet (ELN) recommendations for genetic risk
stratification of acute myeloid leukemia have been widely adopted, but have not yet been�…

Fluorescence in situ hybridization (FISH) of specific DNA probes has become a widely used
technique mostly for chromosome analysis and for studies of the chromosomal location of�…

Several studies demonstrated a gene-density-correlated radial organization of chromosome
territories (CTs) in spherically shaped nuclei of human lymphocytes or lymphoblastoid cells�…

The B-cell survival factors APRIL and BLyS are important for B-cell maturation and activation
and contribute to human autoimmune diseases. Interference with B-cell function by targeting�…

Matricellular proteins participate in the pathogenesis of chronic kidney diseases. We
analyzed glomerular gene expression profiles from patients with proteinuric diseases to�…

Renal proximal tubular epithelial cells, a target of infiltrating T cells during renal allograft
rejection, may be protected from this injury by the cell surface protein CD274 (also termed�…