Multiple studies suggested using different miRNAs as biomarkers for prognosis of
hepatocellular carcinoma (HCC). We aimed to assemble a miRNA expression database�…

In September 1998 the workshop for “Conditional Genome Alterations” in Cold Spring
Harbor had a simple but important take-home message:“Cre works”(Rossant and McMahon�…

Single-molecule force spectroscopy has emerged as a powerful tool to investigate the forces
and motions associated with biological molecules and enzymatic activity. The most common�…

THE endothelial cell-specific vascular endothelial growth factor (VEGF) 1–5 and its cellular
receptors Flt-1 (refs 6, 7) and Flk-1 (refs 8, 9) have been implicated in the formation of the�…

Several newly generated mouse embryonic stem (ES) cell lines were tested for their ability
to produce completely ES cell-derived mice at early passage numbers by ES cell<==>�…

Cancer hallmark genes are responsible for the most essential phenotypic characteristics of
malignant transformation and progression. In this study, our aim was to estimate the�…

The developmental potential of embryonic stem (ES) cells versus 3. 5 day inner cell mass
(ICM) was compared after aggregation with normal diploid embry os and with�…

New therapeutic targets for noncognitive reductions in energy intake, absorption, or storage
are crucial given the worldwide epidemic of obesity. The gut microbial community�…

Ionospheres provides a comprehensive description of the physical, plasma and chemical
processes controlling the behavior of ionospheres. The relevant transport equations and�…

The trophoblast cell lineage is essential for the survival of the mammalian embryo in utero.
This lineage is specified before implantation into the uterus and is restricted to form the fetal�…