DNA microarrays have made it possible to estimate the level of expression of thousands of
genes for a sample of cells. Although biomedical investigators have been quick to adopt this�…

Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular�…

Purpose To provide recommendations on appropriate use of breast tumor biomarker assay
results to guide decisions on adjuvant systemic therapy for women with early-stage invasive�…

Despite years of research and hundreds of reports on tumor markers in oncology, the
number of markers that have emerged as clinically useful is pitifully small. Often initially�…

Despite years of research and hundreds of reports on tumor markers in oncology, the
number of markers that have emerged as clinically useful is pitifully small. Often, initially�…

Purpose.—To update key recommendations of the American Society of Clinical Oncology
(ASCO)/College of American Pathologists (CAP) human epidermal growth factor receptor 2�…

Abstract Background The Reporting Recommendations for Tumor Marker Prognostic
Studies (REMARK) checklist consists of 20 items to report for published tumor marker�…

Purpose To update the American Society of Clinical Oncology (ASCO)/College of American
Pathologists (CAP) guideline recommendations for human epidermal growth factor receptor�…

Purpose.—To update the American Society of Clinical Oncology-College of American
Pathologists (ASCO-CAP) recommendations for human epidermal growth factor receptor 2�…

Purpose To develop a guideline to improve the accuracy of human epidermal growth factor
receptor 2 (HER2) testing in invasive breast cancer and its utility as a predictive marker�…