Substantial evidence indicates that women report greater fear and are more likely to develop
anxiety disorders than men. Women's greater vulnerability for anxiety disorders can be partly�…

Pathological accumulation of abnormally phosphorylated tau protein in astrocytes is a
frequent, but poorly characterized feature of the aging brain. Its etiology is uncertain, but its�…

Post-traumatic stress disorder (PTSD) is a highly prevalent, often chronic and disabling
psychiatric disorder that is associated with significant adverse health and life consequences�…

Abstract We developed the Genomic Regions Enrichment of Annotations Tool (GREAT) to
analyze the functional significance of cis-regulatory regions identified by localized�…

Genetic evidence strongly supports the view that Aβ amyloid production is central to the
cause of Alzheimer's disease. The kinetics, compartmentation, and form of Aβ and its�…

Humans differ from other animals in many aspects of anatomy, physiology, and behaviour;
however, the genotypic basis of most human-specific traits remains unknown. Recent whole�…

Women have consistently higher prevalence rates of anxiety disorders, but less is known
about how gender affects age of onset, chronicity, comorbidity, and burden of illness�…

Inhibition of neocortical β-amyloid (Aβ) accumulation may be essential in an effective
therapeutic intervention for Alzheimer's disease (AD). Cu and Zn are enriched in Aβ deposits�…

Background Immunohistochemical markers are often used to classify breast cancer into
subtypes that are biologically distinct and behave differently. The aim of this study was to�…

Tumor recurrence is a leading cause of cancer mortality. Therapies for recurrent disease
may fail, at least in part, because the genomic alterations driving the growth of recurrences�…