BACKGROUND: A number of formats for nucleic acid hybridization have been developed to
identify DNA and RNA sequences that are involved in cellular processes and that aid in the�…

With the introduction of simple and relatively inexpensive methods for labeling nucleic acids
with nonradioactive labels, doors have been opened that enable nucleic acid hybridization�…

An important consideration in the design of oligonucleotide probes for homogeneous
hybridization assays is the efficiency of energy transfer between the fluorophore and�…

The use of fluorescent nucleic acid hybridization probes that generate a fluorescence signal
only when they bind to their target enables real-time monitoring of nucleic acid amplification�…

We describe a multiplex nucleic acid assay that identifies and determines the abundance of
four different pathogenic retroviruses (HIV-1, HIV-2, and human T-lymphotrophic virus types I�…

We describe wavelength-shifting molecular beacons, which are nucleic acid hybridization
probes that fluoresce in a variety of different colors, yet are excited by a common�…

We demonstrate that single-nucleotide differences in a DNA sequence can be detected in
homogeneous assays using molecular beacons. In this method, the region surrounding the�…

In this work, we characterize genes in Mycobacterium tuberculosis that are regulated by
IdeR (i ron‐de pendent r egulator), an iron‐responsive DNA‐binding protein of the DtxR�…

ABSTRACT A collection of Aspergillus fumigatus mutants highly resistant to itraconazole
(RIT) at 100 μg ml− 1 were selected in vitro (following UV irradiation as a preliminary step) to�…

The mechanism of transport of mRNA-protein (mRNP) complexes from transcription sites to
nuclear pores has been the subject of many studies. Using molecular beacons to track�…