We tested the hypothesis that loss of replication control of DNA loci associated with human
centromeres affects the main centromere function, namely, ensuring proper sister chromatid�…

We demonstrate a significant association between longer CAG repeats in the
hKCa3/KCNN3 calcium-activated potassium channel gene and schizophrenia in Israeli�…

Pluripotency and proliferative capacity of human embryonic stem cells (hESCs) make them a
promising source for basic and applied research as well as in therapeutic medicine. The�…

Abnormal recombination between the X and Y chromosomes during meiosis, occurring
outside the pseudoautosomal region, can result in translocation of the SRY gene from the Y�…

A close association usually exists between replication timing of a given locus and its
transcriptional activity: expressed loci replicate early whereas silent ones replicate late�…

E3 ubiquitin ligases (E3s) play essential roles in the maintenance of tissue homeostasis
under normal and stress conditions, as well as in disease states, particularly in cancer�…

BACKGROUND: Peripheral blood lymphocytes of patients with hematological malignancies
or solid tumors, such as renal cell carcinoma or prostate cancer, display epigenetic�…

Since the 1970's stormwater ponds (SWPs) have been used to mitigate the risks of flooding
and pollution posed by stormwater runoff from paved impervious surfaces. SWPs have been�…

Introduction In order to investigate the dynamics of genomic alterations that occur at different
developmental stages in vitro, we examined the chromosome content of human�…

Using fluorescence in situ hybridization (FISH) to interphase nuclei, we examined the
replication timing of 1 allele relative to its counterpart in PHA‐stimulated peripheral blood�…