PURPOSE: Several recent reports of high local recurrence and lymph node metastasis in T1
carcinoma of the rectum prompted us to study the risk factors for lymph node metastasis in�…

Objective: Through a comprehensive review of the Mayo Clinic experience with patients who
had Meckel diverticulum, we sought to determine which diverticula should be removed when�…

Biological systems are characterized by a level of spatial and temporal organization that
often lies beyond the grasp of present day methods. Light-modulated bioreagents, including�…

Objective To determine the clinical and laboratory features of newly diagnosed multiple
myeloma. Patients and Methods Records of all patients in whom multiple myeloma was�…

The use of semiconductor nanocrystals (quantum dots) as fluorescent labels for multiphoton
microscopy enables multicolor imaging in demanding biological environments such as living�…

Calculation of the centroid of the images of individual fluorescent particles and molecules
allows localization and tracking in light microscopes to a precision about an order of�…

Background A monoclonal gammopathy of undetermined significance (MGUS) occurs in up
to 2 percent of persons 50 years of age or older. Reliable predictors of progression have not�…

Background: Descriptive epidemiology of total joint replacement procedures is limited to
annual procedure volumes (incidence). The prevalence of the growing number of�…

Background The prevalence of monoclonal gammopathy of undetermined significance
(MGUS), a premalignant plasma-cell disorder, among persons 50 years of age or older has�…

The POEMS syndrome (coined to refer to polyneuropathy, organomegaly, endocrinopathy,
M protein, and skin changes) remains poorly understood. Ambiguity exists over the features�…