Short-chain dehydrogenases/reductases (SDR)
Revised Manuscript Received March 8, 1995s abstract: Short-chain dehydrogenases/
reductases (SDR) constitute a large protein family. Presently, at least 57 characterized�…
reductases (SDR) constitute a large protein family. Presently, at least 57 characterized�…
[HTML][HTML] Medium-and short-chain dehydrogenase/reductase gene and protein families: the SDR superfamily: functional and structural diversity within a family of�…
KL Kavanagh, H J�rnvall, B Persson…�- Cellular and Molecular�…, 2008 - Springer
Short-chain dehydrogenases/reductases (SDRs) constitute a large family of NAD (P)(H)-
dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms�…
dependent oxidoreductases, sharing sequence motifs and displaying similar mechanisms�…
Short-chain dehydrogenases/reductases (SDR): the 2002 update
U Oppermann, C Filling, M Hult, N Shafqat, X Wu…�- Chemico-biological�…, 2003 - Elsevier
Short-chain dehydrogenases/reductases (SDR) form a large, functionally heterogeneous
protein family presently with about 3000 primary and about 30 3D structures deposited in�…
protein family presently with about 3000 primary and about 30 3D structures deposited in�…
Cloning, structure, and expression of the mitochondrial cytochrome P-450 sterol 26-hydroxylase, a bile acid biosynthetic enzyme
S Andersson, DL Davis, H Dahlb�ck, H J�rnvall…�- Journal of Biological�…, 1989 - ASBMB
The conversion of cholesterol into bile acids in the liver represents the major catabolic
pathway for the removal of cholesterol from the body. In this complex biosynthetic pathway�…
pathway for the removal of cholesterol from the body. In this complex biosynthetic pathway�…
Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties�…
B Mannervik, P Alin, C Guthenberg…�- Proceedings of the�…, 1985 - National Acad Sciences
The major isoenzymes of cytosolic glutathione transferase (EC 2.5. 1.18) from rat, mouse,
and man are shown to share structural and catalytic properties that can be used for species�…
and man are shown to share structural and catalytic properties that can be used for species�…
Characterization of a gastrin releasing peptide from porcine non-antral gastric tissue
TJ McDonald, H J�rnvall, G Nilsson, M Vagne…�- Biochemical and�…, 1979 - Elsevier
A heptacosapeptide with potent gastrin releasing activity has been isolated from porcine non-
antral gastric and intestinal tissue. The amino acid sequence suggested from a preliminary�…
antral gastric and intestinal tissue. The amino acid sequence suggested from a preliminary�…
The human antimicrobial and chemotactic peptides LL-37 and α-defensins are expressed by specific lymphocyte and monocyte populations
B Agerberth, J Charo, J Werr, B Olsson…�- Blood, The Journal�…, 2000 - ashpublications.org
We identified antibacterial components in human T and natural killer (NK) cells by using
freshly isolated lymphocytes enriched for T and NK cells as starting material. After growing�…
freshly isolated lymphocytes enriched for T and NK cells as starting material. After growing�…
Galanin—a novel biologically active peptide from porcine intestine
K Tatemoto, � R�kaeus, H J�rnvall, TJ McDonald…�- FEBS�…, 1983 - Wiley Online Library
The isolation of a novel biologically active peptide, designated galanin, is described. The
peptide was discovered by the detection of its C‐terminal amide structure in porcine�…
peptide was discovered by the detection of its C‐terminal amide structure in porcine�…
Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons.
M Trupp, M Ryd�n, H J�rnvall, H Funakoshi…�- The Journal of cell�…, 1995 - rupress.org
Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic polypeptide, distantly
related to transforming growth factor-beta (TGF-beta), originally isolated by virtue of its ability�…
related to transforming growth factor-beta (TGF-beta), originally isolated by virtue of its ability�…
[HTML][HTML] Critical residues for structure and catalysis in short-chain dehydrogenases/reductases
Short-chain dehydrogenases/reductases form a large, evolutionarily old family of NAD
(P)(H)-dependent enzymes with over 60 genes found in the human genome. Despite low�…
(P)(H)-dependent enzymes with over 60 genes found in the human genome. Despite low�…