Historically, studies of disseminated tumour cells in bone marrow and circulating tumour
cells in peripheral blood have provided crucial insights into cancer biology and the�…

Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of�…

Recent technological advances have enabled the detection and detailed characterization of
circulating tumor cells (CTC) and circulating tumor DNA (ctDNA) in blood samples from�…

The purpose of this study was to classify breast carcinomas based on variations in gene
expression patterns derived from cDNA microarrays and to correlate tumor characteristics to�…

Human breast tumours are diverse in their natural history and in their responsiveness to
treatments. Variation in transcriptional programs accounts for much of the biological diversity�…

We used cDNA microarrays to explore the variation in expression of approximately 8,000
unique genes among the 60 cell lines used in the National Cancer Institute's screen for anti�…

cDNA microarrays and a clustering algorithm were used to identify patterns of gene
expression in human mammary epithelial cells growing in culture and in primary human�…

Gene amplifications and deletions frequently contribute to tumorigenesis. Characterization
of these DNA copy-number changes is important for both the basic understanding of cancer�…

Metastasis is a multistep process responsible for most cancer deaths, and it can be
influenced by both the immediate microenvironment (cell–cell or cell–matrix interactions)�…

Genomic DNA copy number alterations are key genetic events in the development and
progression of human cancers. Here we report a genome-wide microarray comparative�…