Antiplatelet agents for preventing pre‐eclampsia and its complications
L Duley, S Meher, KE Hunter…�- …�of systematic reviews, 2019 - cochranelibrary.com
Background Pre‐eclampsia is associated with deficient intravascular production of
prostacyclin, a vasodilator, and excessive production of thromboxane, a vasoconstrictor and�…
prostacyclin, a vasodilator, and excessive production of thromboxane, a vasoconstrictor and�…
Breast cancer screening using tomosynthesis or mammography: a meta-analysis of cancer detection and recall
Background Tomosynthesis approximates a 3D mammogram of the breast, reducing
parenchymal overlap that masks cancers or creates false “lesions” on 2D mammography�…
parenchymal overlap that masks cancers or creates false “lesions” on 2D mammography�…
Deferred cord clamping, cord milking, and immediate cord clamping at preterm birth: a systematic review and individual participant data meta-analysis
AL Seidler, M Aberoumand, KE Hunter, A Barba…�- The Lancet, 2023 - thelancet.com
Background Umbilical cord clamping strategies at preterm birth have the potential to affect
important health outcomes. The aim of this study was to compare the effectiveness of�…
important health outcomes. The aim of this study was to compare the effectiveness of�…
IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion
Innate immune cells can constitute a substantial proportion of the cells within the tumor
microenvironment and have been associated with tumor malignancy in patients and animal�…
microenvironment and have been associated with tumor malignancy in patients and animal�…
Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells
BR Williams, VR Prabhu, KE Hunter, CM Glazier…�- Science, 2008 - science.org
Aneuploidy, an incorrect number of chromosomes, is the leading cause of miscarriages and
mental retardation in humans and is a hallmark of cancer. We examined the effects of�…
mental retardation in humans and is a hallmark of cancer. We examined the effects of�…
Association between oxygen saturation targeting and death or disability in extremely preterm infants in the neonatal oxygenation prospective meta-analysis�…
LM Askie, BA Darlow, N Finer, B Schmidt, B Stenson…�- Jama, 2018 - jamanetwork.com
Importance There are potential benefits and harms of hyperoxemia and hypoxemia for
extremely preterm infants receiving more vs less supplemental oxygen. Objective To�…
extremely preterm infants receiving more vs less supplemental oxygen. Objective To�…
Searching clinical trials registers: guide for systematic reviewers
Systematic reviews should incorporate as much relevant evidence as possible to reduce
bias and research waste and increase reliability of results. Clinical trials registers are a key�…
bias and research waste and increase reliability of results. Clinical trials registers are a key�…
Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development
SM Pyonteck, BB Gadea, HW Wang, V Gocheva…�- Oncogene, 2012 - nature.com
Tumor-associated macrophages have recently emerged as a key regulatory cell type during
cancer progression, and have been found to promote tumor malignancy in the majority of�…
cancer progression, and have been found to promote tumor malignancy in the majority of�…
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix
During the process of tumor progression, cancer cells can produce the requisite growth-and
invasion-promoting factors and can also rely on noncancerous cells in the tumor�…
invasion-promoting factors and can also rely on noncancerous cells in the tumor�…
A guide to prospective meta-analysis
In a prospective meta-analysis (PMA), study selection criteria, hypotheses, and analyses are
specified before the results of the studies related to the PMA research question are known�…
specified before the results of the studies related to the PMA research question are known�…