We have chosen tumors of the uterine cervix as a model system to identify chromosomal
aberrations that occur during carcinogenesis. A phenotype/genotype correlation was�…

We have analyzed 30 cases of advanced‐stage cervical squamous cell carcinoma (stages
IIb–IV) by comparative genomic hybridization (CGH). The most consistent chromosomal gain�…

Comparative genomic hybridization was used to screen the DNA extracted from
histologically defined tissue sections from consecutive stages of colorectal carcinogenesis�…

Fluorescence in situ hybridization techniques allow the visualization and localization of DNA
target sequences on the chromosomal and cellular level and have evolved as exceedingly�…

Squamous cell carcinomas of the anus are rare neoplasias that account for about 3% of
large bowel tumours. Infections with human papillomaviruses are frequently detected in�…

The expression level of strometysin‐3 (ST3) mRNA was analyzed by in situ hybridization of
formalin‐fixed, paraffin‐embedded primary breast‐tumor samples from 76 patients. Digital�…

This paper describes the investigation of nuclear DNA content and p53 immunoreactivity in
normal mucosa (n= 25), mildly (n= 15), moderately (n= 28) and severely atypical (n= 22)�…

Matrix metalloproteinases are believed to play an important role in tumor progression,
invasion and metastasis. In order to investigate if the expression of stromelysin-3 (ST3)�…

Proliferating cell nuclear antigen (PCNA), nuclear DNA content and mutant p53
overexpression were studied by means of image cytometry and immunohistochemistry�…

Primary fallopian tube carcinoma (PFTC) is a rare and highly aggressive tumor. Twelve
cases of PFTC (stages IA to IV) were analyzed by comparative genomic hybridization. The�…