Cloning and sequencing of the complementary DNA for platelet-derived endothelial cell
growth factor indicates that it is a novel factor distinct from previously characterized proteins�…

Human transforming growth factor beta 1 (TGF-beta 1) was purified as a latent high Mr
complex from human platelets by a six-step procedure. Analysis by sodium dodecyl sulfate�…

The Alzheimer A beta amyloid peptide (A beta) is the principal proteinaceous component of
amyloid associated with Alzheimer disease (AD). We have determined the relative�…

Monoglyceride lipase catalyzes the last step in the hydrolysis of stored triglycerides in the
adipocyte and presumably also complements the action of lipoprotein lipase in degrading�…

Background Shedding microvesicles are membrane released vesicles derived directly from
the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin�…

TGF-B occurs in a latent complex of high M,. We report the cDNA cloning and an initial
structural and functional characterization of a component of the large latent TGF-pl complex�…

A genetic approach is described to clarify the IgG‐binding properties of the N‐terminal
portion of staphylococcal protein A (region E). Several gene fragments, encoding region E or�…

Smad proteins regulate gene expression in response to TGFβ signaling. Here we present
evidence that Smad7 interacts with the transcriptional coactivator p300, resulting in�…

Vascular endothelial growth factor B (VEGF-B) is expressed in various tissues, especially
strongly in the heart, and binds selectively to one of the VEGF receptors, VEGFR-1. The two�…

Transthyretin (TTR) familial amyloid polyneuropathies (FAP) are autosomal dominant
devastating afflictions. They were first described in Portugal, later in Japan and Sweden and�…